منابع مشابه
Gut Reaction to Wnt Signaling in Worms
its daughter cells differentiate like MS and no longer produce gut (Goldstein 1993). Further nongenetic ma-Department of Molecular, Cellular, and Developmental Biology nipulations of cultured embryonic cells have demonstrated that P 2 is the source of this signal and that the University of Colorado Boulder, Colorado 80309-0347 position of P 2 relative to EMS determines which daughter of EMS pro...
متن کاملInteraction of viral oncogenic proteins with the Wnt signaling pathway
It is estimated that up to 20% of all types of human cancers worldwide are attributed to viruses. The genome of oncogenic viruses carries genes that have protein products that act as oncoproteins in cell proliferation and transformation. The modulation of cell cycle control mechanisms, cellular regulatory and signaling pathways by oncogenic viruses, plays an important role in viral carcinogenes...
متن کاملThe Canonical Wnt Signaling (Wnt/β-Catenin Pathway): A Potential Target for Cancer Prevention and Therapy
Precise regulation of signal transduction pathways is crucial for normal animal development and for maintaining cellular and tissue homeostasis in adults. The Wnt/Frizzled-mediated signaling includes canonical and non-canonical signal transduction pathways. Upregulation or downregulation of the canonical Wnt-signaling (or the Wnt/β-Catenin signal transduction) leads to a variety of human diseas...
متن کاملWnt signaling in cancer.
Aberrant regulation of the Wnt signaling pathway is a prevalent theme in cancer biology. From the earliest observation that Wnt overexpression could lead to malignant transformation of mouse mammary tissue to the most recent genetic discoveries gleaned from tumor genome sequencing, the Wnt pathway continues to evolve as a central mechanism in cancer biology. This article summarizes the evidence...
متن کاملWnt signaling.
The use of Wnt ligands for signaling between cells is a conserved feature of metazoan development. Activation of Wnt signal transduction pathways upon ligand binding can regulate diverse processes including cell proliferation, migration, polarity, differentiation and axon outgrowth. A 'canonical' Wnt signaling pathway has been elucidated in vertebrate and invertebrate model systems. In the cano...
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ژورنال
عنوان ژورنال: Organogenesis
سال: 2008
ISSN: 1547-6278,1555-8592
DOI: 10.4161/org.4.2.5854